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Articles by Ben Readhead
miR155 regulation of behavior, neuropathology, and cortical transcriptomics in Alzheimer's disease
Abstract MicroRNAs are recognized as important regulators of many facets of physiological brain function while also being implicated in the pathogenesis of several neurological disorders. Dysregulation of miR155 is widely reported across a variety of neurodegenerative conditions, including Alzheimer’s disease (AD), Parkinson’s disease, amyotrophic lateral sclerosis, and traumatic brain injury.
Do infections have a role in the pathogenesis of Alzheimer disease?
Abstract The idea that infectious agents in the brain have a role in the pathogenesis of Alzheimer disease (AD) was proposed nearly 30 years ago. However, this theory failed to gain substantial traction and was largely disregarded by the AD research community for many years. Several recent discoveries have reignited interest in the infectious theory of AD, culminating in a debate on the topic at the Alzheimer’s Association International Conference (AAIC) in July 2019.
Clarifying the Potential Role of Microbes in Alzheimer’s Disease
We thank authors Jeong and Liu for their investment of time in formulating their Letter. Here we respond to their comments. To read this article in full you will need to make a payment Purchase one-time access Read-It-Now Purchase access to all full-text HTML articles for 6 or 36 hr at a low cost. Click here to explore this opportunity. Subscribe to Neuron References Jeong H.-H. Liu Z. Are HHV-6A and HHV-7 really more abundant in Alzheimer’s disease?. Neuron. 2019; 104 (): 1034-1035 Mohorianu I.
Multiscale Analysis of Independent Alzheimer’s Cohorts Finds Disruption of Molecular, Genetic, and Clinical Networks by Human Herpesvirus
References Auton A. Brooks L.D. Durbin R.M. Garrison E.P. Kang H.M. Korbel J.O. Marchini J.L. McCarthy S. McVean G.A. Abecasis G.R. 1000 Genomes Project Consortium A global reference for human genetic variation. Nature. 2015; 526: 68-74 Agostini S. Mancuso R. Baglio F. Cabinio M. Hernis A. Guerini F.R. Calabrese E. Nemni R. Clerici M. Lack of evidence for a role of HHV-6 in the pathogenesis of Alzheimer’s disease. J. Alzheimers Dis. 2016; 49: 229-235 Albright A.V. Lavi E. Black J.B. Goldberg S.
Rapid Therapeutic Recommendations in the Context of a Global Public Health Crisis using Translational Bioinformatics Approaches: A proof-of-concept study using Nipah Virus Infection
Rapid Therapeutic Recommendations in the Context of a Global Public Health Crisis using Translational Bioinformatics Approaches: A proof-of-concept study using Nipah Virus Infection Khader Shameer, Kipp W Johnson, Ben Readhead, Benjamin Glicksberg, Claire McCallum, Amjesh R, Jamie Hirsch, Kevin Bock, John Chelico, Negin Hajizadeh, Michael Oppenheim, Joel Dudley bioRxiv 333021; doi: https://doi.org/10.1101/333021
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