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Benjamin Brennan on Muck Rack

Benjamin Brennan

As seen in: Nature, Wiley Online Library, BMJ Open, Cell Press, The Michigan Daily, The Independent Review
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Articles

An Integrated Oxygen-Supplying Device and Predictive Multiphysics Model for Extended Ambient Transport of Insulin-Producing Cells

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By Daniel A. Domingo-Lopez, Ruth Tarpey, Benjamin Brennan
| Wiley Online Library Verified
1 Introduction Cell therapies and advanced therapeutic medicinal products (ATMPs), such as islet transplantation, represent the next pillar in the healthcare market, with the potential to replace or regenerate damaged tissues and treat a wide range of chronic and currently incurable diseases [1], including Type 1 Diabetes Mellitus.
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Conserved pathogenesis of ancestral and contemporary Oropouche virus strains in a murine pregnancy model

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By Krista Gunter, James Bowen, Andrew Clarke, Melanie McFarlane, Curtis Witt, Lisa Rogers, David M. Aronoff, Andrew M. Lunel, Jay Vornhagen, Benjamin Brennan, Natasha L. Tilston, Dorcus C. A. Omoga, Stephanie Pozuelos, Henry Giesel
| Nature Verified
Abstract Oropouche virus (OROV) is an emerging orthobunyavirus responsible for widespread outbreaks across South and Central America. Recent reports of congenital disease have raised urgent concerns regarding the potential risk of OROV infection during pregnancy. Here, we establish an in vivo murine model of OROV vertical transmission using the ancestral (prototype) strain BeAn19991 in immunocompetent C57BL/6 J mice.
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Multi-omics analysis of SFTS virus infection in Rhipicephalus microplus cells reveals antiviral tick factors - Nature Communications

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By Quan Gu, Douglas Lamont, Pietro Scaturro, Benjamin Brennan, Charlotte Flory, Mazigh Fares, Alan Score
| Nature Verified
Abstract The increasing prevalence of tick-borne arboviral infections worldwide necessitates advanced control strategies, particularly those targeting vectors, to mitigate the disease burden. However, the cellular interactions between arboviruses and ticks, especially for negative-strand RNA viruses, remain largely unexplored.
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