Benjamin Pham

Editor’s summary Structured Abstract Abstract Supplementary Materials References and Notes Information & Authors Metrics & Citations Check Access References Figures Tables Media Share Editor’s summary Maintaining the body’s protective barriers requires a fine balance between epithelial cell division and maturation. However, the protein modifications that tune this balance are incompletely understood. Working in human organoids and mouse models, Winge et al.

Inhibitors of the renin-angiotensin-aldosterone system (RAAS) are fundamental therapies in the management of primary hypertension across multiple guidelines.1-4 Among these, angiotensin-converting enzyme inhibitors (ACEIs) have traditionally been preferred as first-line agents owing to their well-established efficacy, long history of use, and low cost.5 In contrast, angiotensin II receptor blockers (ARBs) are often positioned as alternatives, typically reserved for patients who are intolerant...