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Lisa Ko on Muck Rack

Lisa Ko

  • Writer, Editor and Content Manager, Freelance
New York
As seen in: Medium, The New York Times, Daily Mail, Nature, The Washington Post, TIME, BuzzFeed, PBS, Business Wire, People and
MEMORY PIECE on shelves now Author of THE LEAVERS, triple Scorpio, New Yorker
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Articles

Ubiquitin-like proteins NEDD8 and SUMO2 control epithelial homeostasis, regeneration, and inflammation

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By Grace A. Pan, Seok-Jin Kim, K.P. Lamers, Leandra V. Jackrazi, Douglas Porter, Suhas Srinivasan, Vanessa Lopez-Pajares, Dayan Li, Benjamin Pham Verified, Aubrey Houser, Robin Meyers, Lisa Ko, Luca Ducoli, Weili Miao, Lindsey Meservey, Brian J. Zarnegar, Mark Smith, Andrew L. Ji, Michael T. Longaker, Paul A. Khavari, Mårten C. G. Winge, Spencer H. Cha
| Science Magazine Verified
Editor’s summary Structured Abstract Abstract Supplementary Materials References and Notes Information & Authors Metrics & Citations Check Access References Figures Tables Media Share Editor’s summary Maintaining the body’s protective barriers requires a fine balance between epithelial cell division and maturation. However, the protein modifications that tune this balance are incompletely understood. Working in human organoids and mouse models, Winge et al.
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Functional analysis of cancer-associated germline risk variants - Nature Genetics

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By Laura Kellman, Suhas Srinivasan, Margaret Guo, Lisa Ko, Smarajit Mondal, Ibtihal Elfaki, Stephen Montgomery, Ronald L. Shanderson
| Nature Verified
Abstract Single-nucleotide variants (SNVs) in regulatory DNA are linked to inherited cancer risk. Massively parallel reporter assays of 4,041 SNVs linked to 13 neoplasms comprising >90% of human malignancies were performed in pertinent primary human cell types and then integrated with matching chromatin accessibility, DNA looping and expression quantitative trait loci data to nominate 380 potentially regulatory SNVs and their putative target genes.
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DDX50 cooperates with STAU1 to effect stabilization of pro-differentiation RNAs

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By Weili Miao, Douglas Porter, Zurab Siprashvili, Ian Ferguson, Luca Ducoli, Duy Nguyen, Lisa Ko, Vanessa Lopez-Pajares, Suhas Srinivasan, Audrey W. Hong, Yen-Yu Yang, Zhongwen Cao, Robin Meyers, Jordan Meyers, Yinsheng Wang, Paul A. Khavari, Shiying Tao
| Cell Reports Verified
Keywords RNA helicase DDX50 tissue differentiation glucose STAU1 mRNA stability Research topic(s) CP: Molecular biology Introduction RNA-binding proteins (RBPs) can promote either RNA stability or decay to mediate post-transcriptional control of RNA expression in ways important for cell fate.1,2 The DExD/H-box RNA helicases comprise a family of RBPs that exert diverse impacts on RNA, including on RNA translation, folding, and subcellular localization,3 but their impacts on RNA stability are...
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