Bhanu Kanth Manne on Muck Rack

Bhanu Kanth Manne

As seen in: Wiley, The Journal of Biological Chemistry
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Articles

COVID‐19 patients exhibit reduced procoagulant platelet responses

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By Frederik Denorme, Bhanu Kanth Manne, Irina Portier, Aaron C. Petrey
| Wiley
Abstract Background Emerging evidence implicates dysfunctional platelet responses in thrombotic complications in COVID‐19 patients. Platelets are important players in inflammation‐induced thrombosis. In particular, procoagulant platelets support thrombin generation and mediate thromboinflammation. Objectives To examine if procoagulant platelet formation is altered in COVID‐19 patients and if procoagulant platelets contribute to pulmonary thrombosis.
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Gq pathway regulates proximal C-type lectin-like receptor-2 (CLEC-2) signaling in platelets

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By Rachit Badolia, Vaishali Inamdar, Bhanu Kanth Manne, Carol A. Dangelmaier
| The Journal of Biological Chemistry Verified
Platelets play a key role in the physiological hemostasis or pathological process of thrombosis. Rhodocytin, an agonist of the C-type lectin-like receptor-2 (CLEC-2), elicits powerful platelet activation signals in conjunction with Src family kinases (SFKs), spleen tyrosine kinase (Syk), and phospholipase ?2 (PLC?2).
Open in Who Shared Issue with article?

Gq pathway regulates proximal C-type lectin-like receptor 2 (CLEC-2) signaling in platelets

|
By Carol A. Dangelmaier, Rachit Badolia, Vaishali Inamdar, Bhanu Kanth Manne
| The Journal of Biological Chemistry Verified
Platelets play a key role in the physiological hemostasis or pathological process of thrombosis. Rhodocytin, an agonist of the C-type lectin like receptor-2 (CLEC-2), elicits powerful platelet activation signals in conjunction with Src family kinases (SFKs), spleen tyrosine kinase (Syk), and phospholipase ?2 (PLC?2).
Open in Who Shared Issue with article?
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