Bing-jia Yan on Muck Rack

Bing-jia Yan

As seen in: Frontiers in Immunology
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Identification of antibodies against phospholipase A2 receptor peptides in PLA2R-associated membranous nephropathy with negative circulating anti-PLA2R antibodies

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By Miao Wang, Liu Chen Verified, Jin-Ying Wang, Lei Liu, Zhao Cui, Ming-Hui Zhao, Bing-jia Yan
| Frontiers in Immunology
Abstract Background: About 30% of patients with phospholipase A2 receptor (PLA2R) associated membranous nephropathy (MN) have negative circulating anti-PLA2R antibodies. We investigated whether these patients harbor antibodies against linear PLA2R peptides, with the aim of improving serological detection. Methods: We synthesized 123 sequential overlapping linear peptides spanning the extracellular region of PLA2R across ten domains.
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