Bingya Xu on Muck Rack

Bingya Xu

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Articles

A testis-specific E3 ubiquitin ligase complex governs spermiogenesis and male fertility - Nature Communications

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By Tiantian Wu, Chaofeng Tu, Yuxuan Feng, Wenying Qu, Jinyi Chen, Huan Wu, Wenxin Gao, Bingya Xu, Xiangling Yu, Mingyuan Bao, Jinfu Xu, Nianchao Zhou, Haoyue Hu, Bing Jiang, Qingsong Xie, Lanlan Meng, Chen Tan, Ge Lin, Cong Shen, Xia Chen, Yueshuai Guo, Tao Zhou, Yuting Liang, Rong Hua, Yunxia Cao, Mingxi Liu, Jun Yu, Xiaoyan Huang, Yue-Qiu Tan, Bo Zheng
| Nature Verified
Abstract The ubiquitin-proteasome system (UPS) represents an evolutionarily conserved machinery governing proteostasis through spatiotemporal regulation of protein degradation. While spermatogenesis involves multilayered regulatory mechanisms spanning translation to dynamic post-translational modifications (PTMs), the identity of UPS-associated E3 ligases orchestrating germ cell-specific protein turnover remains elusive.
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