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Ge Lin

As seen in: Nature, Wiley Online Library, arXiv, Frontiers, MDPI, Genome Medicine, Cell Press, CGTN, Tehran Times, The Journal of Biological Chemistry and
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Articles

Two distinct causes contribute to the low efficiency of human pre-implantation development

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By Zixuan Li, Lizhi Leng, Jinglei Zhai, Xiaowen Wang, Wuling Yang, Shuhui Wang, Haifeng Wan, Shuoping Zhang, Xi Liao, Yuhui Li, Qing Zeng, Yansu Chen, Zhenyu Xiang, Feiyao Liu, Fuchu He, Yun Yang, Hongmei Wang, Xiaoming Xu, Ge Lin, Chun So
| Cell Press Verified
keywords embryonic arrest human embryo pre-implantation development long-term live-cell imaging centrosome spindle chromosome segregation aneuploidy micronuclei endoplasmic reticulum stress response Introduction At the beginning of life, a metaphase II-arrested egg resumes the second meiotic division upon sperm entry, forming the female and male pronucleus (PN).
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Computer Science > Artificial Intelligence

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By Peng Yuan, Ge Lin
| arXiv
arXivLabs is a framework that allows collaborators to develop and share new arXiv features directly on our website. Both individuals and organizations that work with arXivLabs have embraced and accepted our values of openness, community, excellence, and user data privacy. arXiv is committed to these values and only works with partners that adhere to them. Have an idea for a project that will add value for arXiv's community? Learn more about arXivLabs.
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A testis-specific E3 ubiquitin ligase complex governs spermiogenesis and male fertility - Nature Communications

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By Tiantian Wu, Chaofeng Tu, Yuxuan Feng, Wenying Qu, Jinyi Chen, Huan Wu, Wenxin Gao, Bingya Xu, Xiangling Yu, Mingyuan Bao, Jinfu Xu, Nianchao Zhou, Haoyue Hu, Bing Jiang, Qingsong Xie, Lanlan Meng, Chen Tan, Ge Lin, Cong Shen, Xia Chen, Yueshuai Guo, Tao Zhou, Yuting Liang, Rong Hua, Yunxia Cao, Mingxi Liu, Jun Yu, Xiaoyan Huang, Yue-Qiu Tan, Bo Zheng
| Nature Verified
Abstract The ubiquitin-proteasome system (UPS) represents an evolutionarily conserved machinery governing proteostasis through spatiotemporal regulation of protein degradation. While spermatogenesis involves multilayered regulatory mechanisms spanning translation to dynamic post-translational modifications (PTMs), the identity of UPS-associated E3 ligases orchestrating germ cell-specific protein turnover remains elusive.
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