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Biola-Maria Javierre

As seen in: Genome Biology, Cell Press, JoVE- Journal of Visualized Experiments
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Articles by Biola-Maria Javierre

Promoter Capture Hi-C: High-resolution, Genome-wide Profiling of Promoter Interactions

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By Stefan Schoenfelder, Biola-Maria Javierre, Peter Fraser, Mayra Furlan-Magaril
| JoVE- Journal of Visualized Experiments
Promoter Capture Hi-C is designed to specifically enrich Hi-C libraries for interactions involving promoters. These interactions comprise only a subset of ligation products present in a Hi-C library. Capture Hi-C can easily be modified to enrich Hi-C libraries for any genomic region or regions of interest by changing the capture system.
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Long-Range Enhancer Interactions Are Prevalent in Mouse Embryonic Stem Cells and Are Reorganized upon Pluripotent State Transition

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By Epigenetics Programme, Biola-Maria Javierre, Jonathan Cairns, Clara Lopes Novo
| Cell Press Verified
Rewiring of the SE Interactome upon Pluripotent State Transition   Long-Range SE Interactions Are Detected in ESCs, but Not in EpiSCs   Long-Range Regulatory Contacts in ESCs Are Enriched for NANOG Occupancy In recent years, a subset of regulatory elements termed SEs have gained attention across a wide range of research fields (Hnisz et al., 2013xSuper-enhancers in the control of cell identity and disease.
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Chromosome contacts in activated T cells identify autoimmune disease candidate genes

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By Oliver S. Burren, Biola-Maria Javierre, Daniel B Rainbow
| Genome Biology Verified
Blood samples were obtained from healthy donors selected from the Cambridge BioResource. Donors were excluded if they were diagnosed with autoimmune disease or cancer, were receiving immunosuppressants, cytotoxic agents or intravenous immunoglobulin or had been vaccinated or received antibiotics in the 2–4 weeks preceding the blood donation. CD4+ T cells were isolated from whole blood using RosetteSep (STEMCELL technologies, Canada) according to the manufacturer’s instructions.
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Chromosome contacts in activated T cells identify autoimmune disease-candidate genes

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By Oliver S. Burren, Biola-Maria Javierre, Daniel B Rainbow
| BioRxiv
Chromosome contacts in activated T cells identify autoimmune disease-candidate genes Oliver S Burren, Arcadio Rubio Garcia, Biola-Maria Javierre, Daniel B Rainbow, Jonathan Cairns, Nicholas J Cooper, John J Lambourne, Ellen Schofield, Xaquin Castro Dopico, Ricardo C Ferreira, Richard Coulson, Frances Burden, Sophia P Rowlston, Kate Downes, Steven W Wingett, Mattia Frontini, Willem H Ouwehand, Peter Fraser, Mikhail Spivakov, John A Todd, Linda S Wicker, Antony J Cutler, Chris Wallace bioRxiv...
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