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Birger Lindberg Møller

As seen in: Nature, Cell Press
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Articles

Genetic technologies to enhance crop nutritional value under climate change

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By Dominique Van Der Straeten, Mustafa Bulut, Da Cao, Asaph Aharoni, Howarth Bouis, Antonio Granell, Wilhelm Gruissem, Birger Lindberg Møller, Cathie Martin, Holger Puchta, Nese Sreenivasulu, Alain Tissier, Leena Tripathi, Marc Van Montagu, Alisdair R. Fernie
| Nature Verified
Abstract At present, more than 700 million people live with caloric hunger, and more than two billion suffer from micronutrient deficiencies, known as ‘hidden hunger’.
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Tripterygium wilfordii cytochrome P450s catalyze the methyl shift and epoxidations in the biosynthesis of triptonide - Nature Communications

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By Louise Kjaerulff, Dan Staerk, Birger Lindberg Møller, Quinn Kalby Heck
| Nature Verified
Abstract The diterpenoid triepoxides triptolide and triptonide from Tripterygium wilfordii (thunder god wine) exhibit unique bioactivities with potential uses in disease treatment and as a non-hormonal male contraceptives. Here, we show that cytochrome P450s (CYPs) from the CYP71BE subfamily catalyze an unprecedented 18(4→3) methyl shift required for biosynthesis of the abeo-abietane core structure present in diterpenoid triepoxides and in several other plant diterpenoids.
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Plant cytochrome P450 plasticity and evolution

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By Byng J.W, David Nelson Verified, Birger Lindberg Møller, Cecilie Cetti Hansen
| Cell Press Verified
Abstract The superfamily of cytochrome P450 (CYP) enzymes plays key roles in plant evolution and metabolic diversification. This review provides a status on the CYP landscape within green algae and land plants. The 11 conserved CYP clans known from vascular plants are all present in green algae and several green algae-specific clans are recognized. Clan 71, 72, and 85 remain the largest CYP clans and include many taxa-specific CYP (sub)families reflecting emergence of linage-specific pathways.
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