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Brian Barber

As seen in: Cell Reports
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Articles

Modular adjuvant-free pan-HLA-DR-immunotargeting subunit vaccine against SARS-CoV-2 elicits broad sarbecovirus-neutralizing antibody responses

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By Audrey Kassardjian, Eric Sun, Kayluz Frias Boligan, Iga Kucharska, Edurne Rujas, Arif Jetha, Donald R. Branch, Shawn Babiuk, Brian Barber, Jean-Philippe Julien, Jamie Sookhoo, Krithika Muthuraman
| Cell Reports Verified
Kassardjian et al. engineer and characterize a modular vaccine scaffold for the delivery of antigen to MHC class II on antigen-presenting cells. This protein vaccine induces broad sarbecovirus neutralizing antibody responses and protects from SARS-CoV-2 viral challenge independently of adjuvant co-administration.
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