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Brian Geiss

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Articles

AI-assisted protein design to rapidly convert antibody sequences to intrabodies targeting diverse peptides and histone modifications

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By Adi Rotem, Sixian Qi, Aristeidis G Telonis, Gabriel Galindo, Daiki Maejima, Jacob DeRoo, Tatsuya Morisaki, Hallie P. Febvre, Ning Zhao, Soham Ghosh, Christopher Snow, Brian Geiss, Yasuyuki Ohkawa, Yuko Sato, Hiroshi Kimura, Scott R. Burlingham, Gretchen Fixen, Ryan Hasbrook, E. Handly Mayton
| Science Magazine Verified
Abstract Intrabodies are engineered antibodies that function inside living cells, enabling therapeutic, diagnostic, and imaging applications. While powerful, their development has been hindered by challenges associated with their folding, solubility, and stability in the reduced intracellular environment.
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Deciphering the interaction surface between the West Nile virus NS3 and NS5 proteins

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By Brian Geiss, Martin Bisaillon, Département de Biochimie, de Génomique Fonctionnelle
| Microbiology Research
Article metrics loading... /content/journal/acmi/10.1099/acmi.0.000675.v3 Download as PowerPoint /deliver/fulltext/acmi/6/6/acmi000675.v3.html?itemId=/content/journal/acmi/10.1099/acmi.0.000675.v3&mimeType=html&fmt=ahah References Brand C, Geiss BJ, Bisaillon M. Supplement to Deciphering the interaction surface between the West Nile virus NS3 and NS5 proteins Figshare 2024 [View Article] [Google Scholar] Chambers TJ, Hahn CS, Galler R, Rice CM.
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Multiplexed Capillary-Flow Driven Immunoassay for Respiratory Illnesses

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By Jeremy Link, Brian Geiss, John O’Donnell-Sloan, Sierra Curdts
| ACS Publications
Download Hi-Res ImageDownload to MS-PowerPointCite This:Anal. Chem. 2024, XXXX, XXX Terms & Conditions Most electronic Supporting Information files are available without a subscription to ACS Web Editions. Such files may be downloaded by article for research use (if there is a public use license linked to the relevant article, that license may permit other uses).
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