Brian Murphy on Muck Rack

Brian Murphy

Boston
As seen in: Apple Podcasts, MSN, MDPI, University of Virginia, Arabian Business (English), Cleveland Clinic Newsroom, CSO, JD Supra, Kiplinger, SC Media and
Healthcare IT Analyst on HIE, Interoperability
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Articles

The Nucleoside Analog GS-441524 Effectively Attenuates the In Vitro Replication of Multiple Lineages of Circulating Canine Distemper Viruses Isolated from Wild North American Carnivores

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By Brian Murphy, M. Kevin Keel, M. Kevin, Arturo Oliver-Guimera
| MDPI
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
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Mutation leads to hereditary hemochromatosis-induced PCT in man

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By Andrea Lobo, Claire Richmond, Brian Murphy, Marisa Wexler 
| Porphyria News
A rare mutation in the HFE gene, called H63D, was found to be the cause of hereditary hemochromatosis, a condition marked by iron overload, that ultimately led to porphyria cutanea tarda (PCT) in a 21-year-old man in the U.S., a case report shows. This case demonstrates the occurrence of “PCT in the setting of previously undiagnosed HH [hereditary hemochromatosis] caused by [two copies of the] H63D mutation in the HFE gene, which has rarely been reported,” researchers wrote.
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Risk factors, effective treatments for PCT identified in study

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By Patricia Inacio, Claire Richmond, Brian Murphy, Lindsey Shapiro
| Porphyria News
Heavy alcohol consumption and hereditary hemochromatosis, a genetic disorder characterized by iron overload, are the leading risk factors for porphyria cutanea tarda (PCT), the most common form of porphyria, according to a retrospective 35-year follow-up study conducted in Scotland. Disease remission was more commonly achieved by patients who had been treated with a combination of therapeutic phlebotomy, or bloodletting, and antimalarial medications.
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