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Articles by Brian Rayner
Genetic Factors Contributing to the Pathogenesis of Essential Hypertension in Two African Populations
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Genetic Factors Contributing to the Pathogenesis of Essential Hypertension in Two African Populations
Preprint Article Version 1 This version is not peer-reviewed Version 1 : Received: 20 February 2024 / Approved: 20 February 2024 / Online: 20 February 2024 (09:20:43 CET) Kalideen, K.; Rayner, B.; Ramesar, R. Genetic Factors Contributing to the Pathogenesis of Essential Hypertension in Two African Populations. Preprints 2024, 2024021128. https://doi.org/10.20944/preprints202402.1128.v1 Kalideen, K.; Rayner, B.; Ramesar, R.
Advances in Chronic Kidney Disease in Africa
Abstract : Africa, particularly sub-Sharan Africa (SSA), faces major challenges in respect to chronic kidney disease (CKD). There is a rising prevalence due to the combined effects of hypertension, diabetes, and human immunodeficiency virus (HIV) (and the interaction between them) and the effect of apolipoprotein L1 (APOL1) variants on the susceptibility to CKD. Epidemiological data on the prevalence of CKD are of low-to-medium quality, and reliable data are urgently needed for health planning.
Physiological Treatment of Hypertension in Black Patients: Time for Action
Article, see p 2355 Black patients have the highest age-adjusted prevalence of hypertension (57.6% of men and 53.2% of women), and their blood pressure (BP) is less well controlled despite being more likely to be diagnosed, treated, and treated more intensively.1 In 2017, the death rate from hypertension (per 100 000 population) was 23 in White men, 54.1 in Black men, 18.6 in White women, and 37 in Black women, and BP-related cardiovascular-renal complications (stroke, left ventricular...
Body weight and eGFR during dulaglutide treatment in type 2 diabetes and moderate‐to‐severe chronic kidney disease (AWARD‐7)
Abstract In patients with type 2 dibetes and moderate‐to‐severe chronic kidney disease, dulaglutide treatment led to body weight (BW) loss and lesser eGFR decline compared to insulin glargine. As BW may affect muscle mass, creatinine‐based eGFR can be altered independently of kidney function. Cystatin C‐based eGFR is not affected by muscle mass. The objective of this post‐hoc analysis was to determine whether the lesser eGFR decline with dulaglutide was related to BW loss.
Body Weight and eGFR during Dulaglutide Treatment in Type 2 Diabetes and Moderate‐to‐Severe Chronic Kidney Disease (AWARD‐7)
The full text of this article hosted at iucr.org is unavailable due to technical difficulties. BRIEF REPORT Body Weight and eGFR during Dulaglutide Treatment in Type 2 Diabetes and Moderate‐to‐Severe Chronic Kidney Disease (AWARD‐7) Fady T. Botros PhD Corresponding Author E-mail address: botrosft@lilly.com https://orcid.org/0000-0003-1980-4458 Eli Lilly and Company, Indianapolis, IN, USA Correspondence Fady T.
Measuring Flexural Creep of Ceramic Investment Casting Shells
The investment casting process is widely used for the production of small- and medium-sized parts of precision metal castings having complicated geometries. The process starts by dipping a foam or wax pattern in a slurry of ceramic powders (e.g., fused silica, zircon, alumina, etc.). Refractory powders (stucco) are next applied to the slurry coated pattern. The pattern is then removed from the ceramic shell by melting the wax or thermally decomposing the foam.
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