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J. David Spence on Muck Rack

J. David Spence

As seen in: JAMA (The Journal of the American Medical Association), JAMA Network, JAMA: Journal of the American Medical Association, Nutrition & Metabolism, MedPage Today, Canadian Medical Association Journal, Annals of Internal Medicine, Healio, Neurology, JACC (Journal of the American College of Cardiology) and
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Articles

Homocysteine and Myocardial Injury:

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By J. David Spence
| JACC (Journal of the American College of Cardiology)
Introduction In this issue of JACC: Asia, Tan et al1 report on the association of plasma total homocysteine (tHcy) with markers of myocardial injury. They assessed high-sensitivity troponin T, high-sensitivity troponin I, and N-terminal pro-B-type natriuretic peptide. Among 10,871 participants without diagnosed cardiovascular disease (CVD), they found that tHcy was consistently related to myocardial injury.
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Poor results with “Best Medical Therapy” in patients with asymptomatic carotid stenosis

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By J. David Spence
| Annals of Vascular Surgery Verified
In a recent paper in this journal, Oliveira et al.present the poor results of medical therapy in their patients with asymptomatic carotid stenosis (ACS).
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Problems with this review of Vitamin B12

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By J. David Spence
| bmj.com
Dear Editor Sadly, I disagree with most of the highlighted statements in the box. My comments on the statements are shown below each. 1. The clinical picture is the most important factor in assessing the significance of results of blood tests assessing cobalamin (B12) status because there is no “gold standard” test to define deficiency. Comment: B12 deficiency takes a long time to develop; it is a mistake to wait until there are symptoms before treating it.
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