Bruce Miller

Neither genes nor the environment should be studied in isolation in brain health and dementia research. Across Alzheimer’s disease and frontotemporal lobar degeneration, risk and resilience emerge from the interactions of inherited susceptibility, biological embeddings, and exposure to environmental factors accumulated across the lifespan (the exposome)1,2.

Keywords tau protein cleavage PTMs neurodegenerative diseases mass spectrometry proteomics MRM biomarkers therapeutics machine learning Introduction This study was conducted to address knowledge gaps in tauopathies, where a lack of human molecular information hinders patient stratification and therapeutic development.

Whether you sell B-to-C, B-to-B, or Non-profit to Donor, ultimately, everyone is a Consumer. Why? Because everyone responds to brands. This fact was borne out when I received an email from one of my non-profit clients: “Bruce, guess what!” Cindi Johnson wrote. “We received a $100,000 check today for facility improvements.