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Bruno Arruda

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Cancers | Free Full-Text | Resveratrol-Loaded Polymeric Nanoparticles: The Effects of D-α-Tocopheryl Polyethylene Glycol 1000 Succinate (TPGS) on Physicochemical and Biological Properties against Breast Cancer In Vitro and In Vivo

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By Bruno Arruda, Raquel Petrilli, Josimar O. Eloy, Tiago Lima Sampaio
| MDPI
Abstract : Simple Summary Resveratrol is a compound that has demonstrated anti-proliferative effects on several cancer cell lines. However, resveratrol is a lipophilic drug and its therapeutic effect can be improved by encapsulation in polymeric nanoparticles. Furthermore, functionalization of polycaprolactone-based polymeric nanoparticles with the non-ionic surfactant TPGS was reported to reduce drug resistance.
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