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Bylicky M.A on Muck Rack

Bylicky M.A

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Articles

SRSF1 governs progenitor-specific alternative splicing to maintain adult epithelial tissue homeostasis and renewal

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By Tingsheng Yu, Oscar Cazares, Bylicky M.A
| Cell Press Verified
Highlights • SRSF1 governs epithelial progenitor homeostasis • Mis-splicing of SRSF1 targets leads to epithelial progenitor cell death • Cdc45, Incenp, Rif1, and Ncor1 are important targets of SRSF1 Summary Alternative splicing generates distinct mRNA variants and is essential for development, homeostasis, and renewal.
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