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Articles by Cai M. Roberts
A Tale of Two Cell Lines: Characterization of Differential Efficacy of Small Molecule Drugs Cediranib and NU-7441 on Primary Versus Metastatic Colorectal Cancer
1 Introduction Colorectal cancer (CRC) is one of the leading causes of cancer morbidity and mortality amongst both sexes in the United States [1]. Those with a higher risk of CRC, such as those with a family history or those with a genetic predisposition, often receive colon cancer screening at a younger age to identify malignant polyps. However, despite rigorous screening, colon cancer remains a prevalent cause of cancer death.
Putative Biomarkers for Prognosis, Epithelial-to-Mesenchymal Transition, and Drug Response in Cell Lines Representing Oral Squamous Cell Carcinoma Progression
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Shake It Up Baby Now: The Changing Focus on TWIST1 and Epithelial to Mesenchymal Transition in Cancer and Other Diseases
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Cancers | Free Full-Text | Transforming Growth Factor Beta and Epithelial to Mesenchymal Transition Alter Homologous Recombination Repair Gene Expression and Sensitize BRCA Wild-Type Ovarian Cancer Cells to Olaparib
This is an early access version, the complete PDF, HTML, and XML versions will be available soon. Open AccessArticle by 1,*,†, 2,†,‡, 2,§, 2,* and 2 1 Department of Pharmacology, Midwestern University, 555 31st St., Downers Grove, IL 60515, USA 2 Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, 15 York St., New Haven, CT 06510, USA * Authors to whom correspondence should be addressed. † These authors contributed equally to this work.
Transforming Growth Factor Beta and Epithelial to Mesenchymal Transition Alter Homologous Recombination Repair Gene Expression and Sensitize BRCA Wild Type Ovarian Cancer Cells to Olaparib
Preprint Article Version 1 This version is not peer-reviewed Version 1 : Received: 12 April 2023 / Approved: 13 April 2023 / Online: 13 April 2023 (14:30:07 CEST) Roberts, C.M.; Rojas-Alexandre, M.; Hanna, R.E.; Lin, Z.P.; Ratner, E.S. Transforming Growth Factor Beta and Epithelial to Mesenchymal Transition Alter Homologous Recombination Repair Gene Expression and Sensitize BRCA Wild Type Ovarian Cancer Cells to Olaparib. Preprints.org 2023, 2023040327.
Protein kinase Cα-mediated phosphorylation of Twist1 at Ser-144 prevents Twist1 ubiquitination and stabilizes it
Roslyn Tedja‡, Cai M. Roberts‡, Ayesha B. Alvero‡, Carlos Cardenas‡, Yang Yang-Hartwich‡, Sydney Spadinger‡, Mary Pitruzzello‡, Gang Yin§, Carlotta A.
Protein kinase Cα-mediated phosphorylation of Twist1 at Ser-144 prevents Twist1 ubiquitination and stabilizes it
Roslyn Tedja1, Cai M. Roberts1, Ayesha B. Alvero2, Carlos Cardenas1, Yang Yang-Hartwich1, Sydney Spadinger1, Mary Pitruzzello3, Gang Yin4, Carlotta A.
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