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Can Yin

As seen in: Nature, Wiley Online Library, MDPI, Future Medicine
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Articles

Real-world evidence for comparative safety of second-line antihyperglycemic agents in older adults with type 2 diabetes

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By Chungsoo Kim, Fan Bu, Clair Blacketer, Anna Ostropolets, Talita Duarte-Salles, Benjamin Viernes, Thomas Falconer, Andrea Pistillo, Jing Li, Can Yin, Mui Van Zandt, Paul Nagy, Akihiko Nishimura, Evan Minty, Seng Chan You, Mitsuaki Sawano, Shoko Sawano, Ja Young Jeon, Arya Aminorroaya, Lovedeep S Dhingra, Aline F Pedroso, Phyllis Thangaraj, David A. Dorr, Nicole Pratt, Kenneth K. C. Man, Wallis C. Y. Lau, Daniel Morales, Rohan Khera, Martijn J Schuemie, Patrick Ryan, George Hripcsak, Harlan M. Krumholz, Marc A. Suchard, Yuan Lu
| Nature Verified
Abstract As prescribing of newer antihyperglycemic agents expands, there remains limited comparative safety data for older adults—a population particularly vulnerable to adverse drug events and underrepresented in clinical trials. We conduct a multinational cohort study using nine databases from the U.S. and Europe. Among adults aged ≥65, we compare eighteen safety outcomes across four classes of second-line antihyperglycemic agents.
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Citrus cultivar influences the response of rhizosphere microbial communities to drought stress

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By Can Yin, Fuyin Xu, Yanqi Teng, Juyu Chen
| preprints.org
Submitted: 27 October 2025 You are already at the latest version Drought stress profoundly impacts citrus growth and soil health, yet the role of rhizosphere microbial communities in plant drought tolerance remains poorly understood. This study investigated the rhizosphere microbial structure, soil enzymatic activities, and physicochemical properties of drought-tolerant (DR) and drought-sensitive (DS) citrus varieties under drought stress condition.
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Brain Pathology | ISN Neuropathology Journal | Wiley Online Library

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By Yinbo Xiao, Can Yin, Junliang Lu
| Wiley Online Library Verified
Access at https://isn-slidearchive.org/?col=ISN&fol=Archive&file=BPA-24-07-CI-180-3.svs and https://isn-slidearchive.org/?col=ISN&fol=Archive&file=BPA-24-07-CI-180-R4.svs. 1 CLINICAL HISTORY AND IMAGING A 16-year-old girl presented to the clinic with a 2-year history of weight gain. In the last week, she had developed blepharoptosis and blurred vision, with headache and vomiting. She did not have a prior history of tumors. Physical examination showed a moon face, buffalo hump, and purpura.
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