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Infection-acquired protection against SARS-CoV-2 infection and clinical severity by number of prior infections - Nature Communications
Abstract SARS-CoV-2 reinfections have increased since Omicron and are common. Yet, as we approach endemicity, the frequency, severity, and consequences of reinfections remain poorly understood. Using data from a household transmission study in Managua, Nicaragua (2020-2024), we evaluated protection conferred by one, two, and three+ prior infections and compared the severity of first, second, and third+ RT-PCR-confirmed SARS-CoV-2 infections.
Protection Associated with Previous SARS-CoV-2 Infection in Nicaragua
To the Editor: Figure 1.
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