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Carmen Anadon

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Articles

Tumor-infiltrating plasma cell profiling after PD-1 blockade reveals tumor-specific antibodies

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By R. Ryan Meyerhoff, Alan M. Chen, Jenny O’Brien, Carmen Anadon, Koravit Poysungnoen, Jared Lindenberger, Gabor Kemeny, Ricardo A. Chaurio, Tyler Evangelous, Chan Soo Park, Alok Sinha, Eziafa Oduah, Carolyn Glass, Simon Gregory, John Hickey Verified, Priyamvada Acharya, Neal E Ready, Jose R. Conejo-Garcia, José Conejo-Garcia, Wilton B. Williams, Scott J Antonia, Dayan Carrion-Estrada, Liliana Lyniv, Vaibjav Jain, Noah Plappert, Kent Weinhold
| Cell Press Verified
ArticleOnline nowOpen access Affiliations & Notes 1Division of Interventional Radiology, Department of Radiology, Duke University School of Medicine, Durham, NC, 27710, United States of America 2Division of Medical Oncology, Department of Medicine, Duke University School of Medicine, Durham, NC, 27710, United States of America 3Department of Integrative Immunobiology, Duke University School of Medicine, Durham, NC, 27710, United States of America 4Department of Biomedical Engineering, Duke...
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Tumor-infiltrating plasma cell profiling after PD-1 blockade reveals tumor-specific antibodies

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By R. Ryan Meyerhoff, Alan A Chen, Jenny O’Brien, Carmen Anadon, Dayan Carrion-Estrada, Koravit Poysungnoen, Jared Lindenberger, Gabor Kemeny, Liliana Lyniv, Vaibjav Jain, Ricardo A. Chaurio, Noah Plappert, Tyler Evangelous, Chan Soo Park, Alok Sinha, Eziafa Oduah, Carolyn Glass, Kent Weinhold, Simon Gregory, John Hickey Verified, Priyamvada Acharya, Neal E Ready, Jose R. Conejo-Garcia, José Conejo-Garcia, Wilton B. Williams, Scott J Antonia
| Cell Press Verified
ArticleOnline nowOpen access Affiliations & Notes 1Division of Interventional Radiology, Department of Radiology, Duke University School of Medicine, Durham, NC, 27710, United States of America 2Division of Medical Oncology, Department of Medicine, Duke University School of Medicine, Durham, NC, 27710, United States of America 3Department of Integrative Immunobiology, Duke University School of Medicine, Durham, NC, 27710, United States of America 4Department of Biomedical Engineering, Duke...
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Impaired T cell and neoantigen retention in time-serial analysis of metastatic non-small cell lung cancer in patients unresponsive to TIL cell therapy | Nature Cancer

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By Chao Wang, Jamie K Teer, Xiaoxian Liu, Timothy Chan, Vladimir Makarov, Carmen Anadon, Theresa Boyle Verified, Bin Fang, John M. Koomen, Dung-Tsa Chen, Jose R. Conejo-Garcia, José Conejo-Garcia
| Nature Verified
Abstract Cell therapy with tumor-infiltrating lymphocytes (TILs) has yielded durable responses for multiple cancer types, but the causes of therapeutic resistance remain largely unknown. Here multidimensional analysis was performed on time-serial tumor and blood in a lung cancer TIL therapy trial. Using T cell receptor sequencing on both functionally expanded T cells and neoantigen-loaded tetramer-sorted T cells, we identified tumor antigen-specific T cell receptors.
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