Caroline Bivik Stadler on Muck Rack

Caroline Bivik Stadler

As seen in: Cell Press
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Articles

Drosophila Neuroblast Selection Is Gated by Notch, Snail, SoxB, and EMT Gene Interplay

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By Badrul Arefin, Farjana Parvin, Shahrzad Bahrampour, Caroline Bivik Stadler
| Cell Press Verified
Highlights • Drosophila neuroblast selection is an EMT-like process, gated by the Notch pathway • SoxB and Snail family members constitute missing proneural genes • The Notch and EMT pathways intersect via the EMT gene crumbs • The Notch-SoxB-Snail-EMT pathway orchestrates neuroblast selection and delamination Summary In the developing Drosophila central nervous system (CNS), neural progenitor (neuroblast [NB]) selection is gated by lateral inhibition, controlled by Notch signaling and...
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