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Casadora Boone

As seen in: Nature, The Journal of Biological Chemistry
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Articles

CLCC1 promotes hepatic neutral lipid flux and nuclear pore complex assembly - Nature

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By Alyssa J. Mathiowetz, Emily S. Meymand, Güneş Parlakgul, Niek van Hilten, Emily Torres, Leonardo L. Artico, Kirandeep K. Deol, Cody E. Doubravsky, Melissa Roberts, Danielle M. Jorgens, Misun Kang, Casadora Boone, Brian Parks, David W. Morgens, Emily Newman, Yingjiang Zhou, Saswata Talukdar, Michael Grabe, Gregory Ku, Tim P. Levine, Ana Paula Arruda, James A. Olzmann, Stephany P. Pang, Reena Zalpuri, Yaohuan Zhang
| Nature Verified
Abstract Imbalances in lipid storage and secretion lead to hepatic steatosis, the accumulation of lipid droplets in hepatocytes1,2. Our understanding of the mechanisms that govern the channelling of neutral lipids in hepatocytes towards cytosolic lipid droplets or secreted lipoproteins remains incomplete3,4.
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