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Home for a rest: stem cell niche of the postnatal growth plate

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By Julian C Lui, Meyers JL, Barnes KM, Chagin AS
| bioscientifica.com
Introduction Longitudinal bone growth is driven by a process called endochondral ossification, in which growing cartilage is gradually remodeled into newly formed bone (Kronenberg 2003). During embryonic development, this process begins with a condensation of mesenchymal stem cells, which differentiate into type II collagen-producing chondrocytes to form a cartilage mold (Hall & Miyake 2000).
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