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Chandana Barat

As seen in: Nature, Preprints.org
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Articles

AT(N)-Anchored Multimodal Deep Learning for Alzheimer’s Staging: A Taxonomy and Continuous Burden Index for Low-Resource Settings

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By Chandana Barat, Masavir Khliq
| Preprints.org
Submitted: 21 September 2026 Posted: 25 September 2026 You are already at the latest version The global burden of dementia is heavily concentrated in low- and middle-income countries (LMICs), yet biological diagnosis of Alzheimer’s Disease (AD) relies on positron emission tomography (PET) and cerebrospinal fluid (CSF) analysis that are operationally inaccessible in these regions.
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Tau protein- induced sequestration of the eukaryotic ribosome: Implications in neurodegenerative disease

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By Amar Nath Ghosh, Senjuti Banerjee, Sehnaz Ferdosh, Chandana Barat
| Nature Verified
Abstract The human tau is a microtubule-associated intrinsically unstructured protein that forms intraneuronal cytotoxic deposits in neurodegenerative diseases, like tauopathies. Recent studies indicate that in Alzheimer’s disease, ribosomal dysfunction might be a crucial event in the disease pathology. Our earlier studies had demonstrated that amorphous protein aggregation in the presence of ribosome can lead to sequestration of the ribosomal components.
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