Changying Li
Albany
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Supply chain competition and the welfare effects of partial ownership
DATA AVAILABILITY STATEMENT No data is used in this study.
Author Correction: Combination of PARP and KRAS G12D inhibitors enhances therapeutic efficacy by exploiting vulnerabilities in PDAC
Correction to: Nature Communications https://doi.org/10.1038/s41467-026-69695-4, published online 24 February 2026 In the version of the article initially published, in Fig. 1c, in the “AsPC-1” panel, the “Vehicle, DAPI” column was inadvertently duplicated from the “MRTX1133, DAPI” column. The figure has now been corrected using the appropriate DAPI images. This correction has been made to the HTML and PDF versions of the article.
Combination of PARP and KRASG12D inhibitors enhances therapeutic efficacy by exploiting vulnerabilities in PDAC - Nature Communications
Abstract Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive malignancy driven predominantly by KRAS mutations, with KRASG12D present in ~40 % of cases. Although the selective KRASG12D inhibitor MRTX1133 shows promising activity, monotherapy responses are incomplete and resistance emerges rapidly.
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