Changying Zhao
China
As seen in:
Nature,
Wiley Online Library,
ScienceDirect,
BMJ Open,
Frontiers,
MDPI,
ACS Publications,
Royal Society of Chemistry
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Parental gut microbiota dysbiosis is associated with cross-generationally shared DNA methylation patterns and autism-like behaviors in offspring
Abstract Autism spectrum disorder (ASD) is a complex neurodevelopmental condition arising from interactions between genetic and environmental factors. The interplay between the microbiota-gut-brain axis and epigenetics has been implicated in ASD, but the extent of their impact remains unclear. We hypothesized that parental gut microbiota dysbiosis shapes cross-generationally shared DNA methylation patterns and ASD-like phenotypes in offspring.
Autocrine and paracrine regulation of pituitary endocrine cells
Abstract The anterior pituitary gland is an important endocrine organ composed of a variety of key endocrine cells that regulate the functions of peripheral targeted organs, such as growth, development, behavior, lactation, reproduction and the stability of the internal environment and metabolism. This gland also regulates the functions of targeted peripheral endocrine organs, such as the thyroid, adrenal gland and gonads.
The correlation between the trajectory of plasma atherosclerosis-inducing index in the examination population and the risk of developing metabolic dysfunction-associated steatotic liver disease
Abstract Background: Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) is a prevalent metabolic disorder with rising global incidence and substantial clinical implications. The atherogenic index of plasma (AIP), a novel marker of lipid metabolism, has shown potential in predicting metabolic diseases, but its longitudinal association with MASLD remains unclear.
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