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Abstract Hydrogels are widely used in biomedical interfaces, in which effective gas exchange (for example, O2, CO2) within a water-rich environment is essential. However, hydrogels show intrinsically limited air exchange efficiency, owing to the low solubility (C) and diffusivity (D) of non-polar gases in the polar water medium1. This limitation poses a substantial bottleneck in long-term applications, such as wearable health monitors2,3,4,5,6,7 and tissue engineering8,9,10,11,12.
Abstract Cardiac pacemakers are critical for treating heart rhythm disorders, but traditional implants are associated with great risks and complications owing to their invasive nature. Here we introduce a wearable non-invasive ultrasound pacemaker (NUP) that activates engineered sonogenetic ion channels (MscL-G22S) to modulate cardiomyocytes, achieving spatiotemporally controlled precise cardiac pacing.
Coal-based steel plants risk locking in 60 billion tonnes of CO2 by 2070, but most of these emissions can still be avoided at moderate cost. Steel need not be hard to decarbonize: policymakers must seize the narrow window to redirect investments towards cleaner alternatives this decade. Recommendations for policy Policymakers need to act now to minimize investments in coal-based steel plants. Many have not yet broken ground and can still be replaced with cleaner alternatives.
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