Chen-Ying Lee

IMMUNOLOGY AND INFLAMMATION Chronic itch linked to skin microbiota. Image credit: National Institute of Allergy and Infectious Diseases. Microbiota linked to chronic itch Chronic itch, or pruritus, is a symptom of inflammatory skin conditions. The cause of chronic itch, which is difficult to treat, is unclear, but one hallmark of chronic itch is the overgrowth of sensory nerves in the skin. Jeremie Delaleu et al.

H. Müller, Anatomisch-physiologische Untersuchungen über die Retina des Menschen und der Wirbelthiere (Verlag von Wilhelm Engelmann, 1856). A. A. Koelliker, G. Busk, T. H. Huxley, Manual of Human Histology (London: Printed for the Sydenham Society, 1853). R.-Y. Cajal, La rétine des vértebres. J. La Cell. 9, e829 (1892). T. Young, On the Mechanism of the Eye, Philosophical Transactions (W. Bulmer and Co., London, 1801). S. T. V. Soemmerring, Icones Oculi Humani (Francofurti ad Moenum: Varrentrapp et Wenner, 1804).

Three decades ago, toxicologist Gary Miller set out to identify chemical exposures that increase Parkinson’s disease risk. “There was really strong evidence that living near farms, drinking well water, and having exposure to pesticides increase the risk,” he recalls. But which chemicals were to blame? The exposome includes every aspect of a person’s environment that could have health impacts over one’s lifetime—factors ranging from chemical exposures to sun exposure to routine exercise and diet.