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Chenghong Yin

As seen in: Nature, MDPI, BioRxiv, Pediatrics, The Lancet, Dove Medical Press, European Journal of Obstetrics & Gynaecology and Reproductive Biology
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Articles

A nested case-control study of air pollution and congenital heart defects via circulating proteins

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By CHEN LIANG, Ruiyang Ding, Shaofei Su, Shuanghua Xie, Jianhui Liu, Tianhe Li, Zhiwei Sun, Ruixia Liu, Junchao Duan, Chenghong Yin
| Nature Verified
Abstract Prenatal air pollution exposure is linked to congenital heart defects (CHD), while the underlying molecular mechanisms remain poorly understood. Here we showed that maternal exposure to PM2.5, PM10, and NO2 was significantly associated with increased CHD risk during the periconception period, with NO2 exhibiting the strongest effect. Moreover, a supervised sparse partial least square model identified pollutant-specific protein signatures in both maternal serum and umbilical cord serum.
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Predicting cesarean delivery as the outcome of a failed labor inductio

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By Yi Feng, Li Zhou Verified, Chenghong Yin, Yingyi Luan
| Dove Medical Press
Back to Journals » International Journal of Women's Health » Volume 17 Authors Feng Y , Luan Y, Zhou L, Yin C Received 12 September 2025 Accepted for publication 24 November 2025 Published 9 December 2025 Volume 2025:17 Pages 5277—5286 DOI https://doi.org/10.2147/IJWH.S567166 Checked for plagiarism Yes Review by Single anonymous peer review Peer reviewer comments 3 Editor who approved publication: Dr Matteo Frigerio Yi Feng,1 Yingyi Luan,2 Li Zhou,1 Chenghong Yin2 1Department of Obstetrics,...
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Maternal exposure to PM2·5 and the risk of fetal congenital heart defects in China: a nationwide nested case-control study

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By Beijing Obstetrics, Beijing Daxing Maternal, Chenghong Yin
| The Lancet Verified
Introduction Rapid urbanisation has intensified public health threats posed by fine particulate matter (PM2·5). In 2021, ambient PM2·5 caused 8·1 million premature deaths globally, incurring US$8·1 trillion in health costs (6·1% of the 2019 global gross domestic product).1,2 Therefore, a substantial reduction in deaths and illnesses attributable to air pollution has been listed in Target 3.9 of the Sustainable Development Goals proposed by the UN.
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