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Articles by Chenxi He
Data-driven catalyst design for direct catalytic N 2 O decomposition
Abstract Catalytic N2O decomposition in the presence of O2 is a key process for addressing environmental challenges, such as greenhouse gas emissions and ozone layer depletion. However, the identification of efficient catalysts for this reaction remains challenging owing to the limitations of conventional methods. In this study, we employ a machine learning approach designed to accelerate the discovery of effective direct N2O decomposition catalysts.
Combined Prognostic Value of Pre-Radiotherapy BMI and NRS-2002 for Overall Survival in Patients with Esophageal Cancer
Back to Journals » Cancer Management and Research » Volume 18 Authors Wu D, Liu Z, He C, Lin B, Zhou W , Shi Q , Wang X Received 14 July 2026 Accepted for publication 18 October 2026 Published 3 November 2026 Volume 2026:18 639380 DOI https://doi.org/10.2147/CMAR.S639380 Checked for plagiarism Yes Review by Single anonymous peer review Peer reviewer comments 2 Editor who approved publication: Professor Harikrishna Nakshatri Danfeng Wu,1,* Zhongli Liu,1,* Chenxi He,2,* Binwei...
National trends in hydrocephalus mortality in the United States, 1999–2024: a serial cross-sectional (ecological) trend analysis
Abstract Background: How did hydrocephalus-attributable mortality trends and disparities evolve in the United States from 1999 to 2024, and what role did the COVID-19 pandemic play in shaping these patterns during and following its onset? Methods: Using national mortality data from the CDC WONDER database (1999–2024), we assessed age-adjusted mortality rates (AAMRs) for hydrocephalus among population aged 0–85+ years.
H3K4me1 directs H3K36me2 and H3K36me3 deposition in land plants - Nature Communications
Abstract Monomethylation of histone 3 lysine 4 (H3K4me1) marks enhancers in mammals. However, the function of H3K4me1 in plants remains largely unclear. Here, we present the genome-wide distribution of H3K4me1 in diverse species across evolution, revealing a distinctive H3K4me1 distribution pattern in land plants.
A geometric shape regularity effect in the human brain
eLife Assessment This important series of studies provides converging results from complementary neuroimaging and behavioral experiments to identify human brain regions involved in representing regular geometric shapes and their core features. Geometric shape concepts are present across diverse human cultures and possibly involved in human capabilities such as numerical cognition and mathematical reasoning.
Nb‐Promoted Pt/MoOx/TiO2 Catalysts for Low‐Temperature CO2 Hydrogenation to Methanol
Conflict of Interest There are no conflicts to declare. Data Availability Statement All relevant data supporting this article have been included as part of . Supporting Information Filename Description chem70390-sup-0001-SuppMat.docx1.5 MB Supporting Information References 1, , , , , , ACS Catal. 2020, 10, 11318. 2, , , , ACS Catal. 2019, 9, 3026. 3, , , , , , Science 2025, 387, eadn9388. 4, , , , , , , , , , , , Nat. Commun. 2019, 10, 5698. 5, , , , , ACS Cent. Sci. 2020, 6, 1657. 6, Catal.
Synergistic Dual‐Gradient Architecture and Vacancy‐Engineered Catalytic Interfaces via p‐Band Modulation for High‐Reversibility Lithium-Sulfur Batteries - He - Advanced Functional Materials - Wiley Online Library
Conflict of Interest The authors declare no conflict of interest. Supporting Information Filename Description adfm70552-sup-0001-SuppMat.docx28.8 MB Supporting Information References 1, , , , , , , , , , , , Adv. Energy Mater. 2019, 9, 1901667. 2, , , , , , , , , , , , , , Joule 2023, 7, 2074. 3, , Nat. Commun. 2012, 3, 1166. 4, , , , , , , , , , , , ACS Nano 2020, 14, 11929. 5, , , , , , , , , Energy Storage Mater. 2024, 67, 103328. 6, , , , , , , , , , Adv. Mater. 2024, 36, 2303610.
Development of a multiple reaction monitoring (MRM)-based LC-MS/MS method for the quantification of post-translational modifications on histone H3 variants in Arabidopsis thaliana
Development of a multiple reaction monitoring (MRM)-based LC-MS/MS method for the quantification of post-translational modifications on histone H3 variants in Arabidopsis thaliana† Background: although the canonical histone H3.1 and its variant H3.3 differ by only four amino acids, they exhibit distinct genome-wide binding patterns and regulate different biological pathways.
A geometric shape regularity effect in the human brain
Abstract The perception and production of regular geometric shapes is a characteristic trait of human cultures since prehistory, whose neural mechanisms are unknown. Behavioral studies suggest that humans are attuned to discrete regularities such as symmetries and parallelism, and rely on their combinations to encode regular geometric shapes in a compressed form.
Projecting dry-wet abrupt alternation across China from the perspective of soil moisture - npj Climate and Atmospheric Science
Abstract Under a warmer climate, the enhancement of dry-wet abrupt alternation (DWAA) risk poses a great challenge for sustainable development. Here, we introduce a novel framework for DWAA detection based on our proposed soil moisture concentration index. By the end of this century, over humid southern China, the shift of soil moisture time series from anomalously wet to anomalously dry pattern, or the other way around, will be more abrupt.
Reshaping Immunosuppressive Tumor Microenvironment Using Ferroptosis/Cuproptosis Nanosensitizers for Enhanced Radioimmunotherapy
Conflict of Interest The authors declare no conflict of interest. Supporting Information Filename Description adfm202409966-sup-0001-SuppMat.docx6.5 MB Supporting Information References 1, , , , , Lancet 2019, 394, 1467. 2, , , , , CA. Cancer. J. Clin. 2023, 73, 233. 3, , , , , , CA. Cancer. J. Clin. 2022, 72, 372. 4, , JAMA, J. Am. Med. Assoc. 2021, 325, 669. 5, , , , , Lancet Gastroenterol. Hepatol. 2022, 7, 262. 6, , , , , , , , , , , , , , , , , , , , , , , , , , , , , , et al., N. Engl. J. Med. 2015, 372, 2509.
Reshaping Immunosuppressive Tumor Microenvironment Using Ferroptosis/Cuproptosis Nanosensitizers for Enhanced Radioimmunotherapy
Conflict of Interest The authors declare no conflict of interest. Supporting Information Filename Description adfm202409966-sup-0001-SuppMat.docx6.5 MB Supporting Information References 1, , , , , Lancet 2019, 394, 1467. 2, , , , , CA. Cancer. J. Clin. 2023, 73, 233. 3, , , , , , CA. Cancer. J. Clin. 2022, 72, 372. 4, , JAMA, J. Am. Med. Assoc. 2021, 325, 669. 5, , , , , Lancet Gastroenterol. Hepatol. 2022, 7, 262. 6, , , , , , , , , , , , , , , , , , , , , , , , , , , , , , et al., N. Engl. J. Med. 2015, 372, 2509.
SMYD5 Is a Ribosomal Methyltransferase That Catalyzes RPL40 Lysine Methylation To Enhance Translation Output and Promote Hepatocellular Carcinoma
Home > UTHealth > GSBS > Student and Faculty Publications > 1609 Student and Faculty Publications Animals, Humans, Mice, Carcinoma, Hepatocellular, Cell Line, Tumor, Histone-Lysine N-Methyltransferase, Liver Neoplasms, Lysine, Methylation, Mice, Nude, Protein Biosynthesis, Ribosomal Proteins, Methyltransferases DOWNLOADS Included in Bioinformatics Commons, Biomedical Informatics Commons, Medical Sciences Commons, Oncology Commons COinS
SMYD5 is a ribosomal methyltransferase that catalyzes RPL40 lysine methylation to enhance translation output and promote hepatocellular carcinoma
Abstract While lysine methylation is well-known for regulating gene expression transcriptionally, its implications in translation have been largely uncharted. Trimethylation at lysine 22 (K22me3) on RPL40, a core ribosomal protein located in the GTPase activation center (GAC), was first reported 27 years ago. Yet, its methyltransferase and role in translation remain unexplored. Here, we report that SMYD5 has robust in vitro activity toward RPL40 K22 and primarily catalyzes RPL40 K22me3 in cells.
Efficient and Lightweight Neural Network for Hard Hat Detection
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A Novel Method of Synthesizing Polymeric Aluminum Ferric Sulfate Flocculant and Preparing Red Mud-Based Ceramsite
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Assessment of birth cohort screening of chronic hepatitis C in colorectal cancer screening patients in British Columbia
Lay summary: Hepatitis C (HCV) is a persistent liver infection that can cause liver damage and cancer. Fortunately, effective antiviral treatments are now available to cure infections and prevent the development of cancer. As a result, British Columbia has recommended HCV screening for individuals born between 1945 and 1964, as this age group has a high infection prevalence of 2.31%. These individuals are routinely screened for colorectal cancer (CRC).
Dynamic control of chromatin-associated m6A methylation regulates nascent RNA synthesis
Highlights • MTC-deposited m6A increases nascent RNA levels from both promoters and enhancers • m6A on RNA 5′-ends recruits nuclear m6A binders/readers such as hnRNP G/YTHDC1 • Loss of m6A or binders/readers exposes RNA to enable binding of Integrator complex • MTC can thus prevent premature termination by Integrator, stimulating RNA synthesis Summary N6-methyladenosine (m6A) methylation is co-transcriptionally deposited on mRNA, but a possible role of m6A on transcription remains poorly...
Collective Asymmetric Total Syntheses of Marine Decahydroquinoline Alkaloid Lepadins A-E, H, and ent-I
Download Hi-Res ImageDownload to MS-PowerPointCite This:Org. Lett.
Post-translational regulation of antiviral innate signaling
The innate immune system initiates immune responses by pattern-recognition receptors (PRR). Virus-derived nucleic acids are sensed by the retinoic acid-inducible gene I (RIG-I)-like receptor (RLR) family and the toll-like receptor (TLR) family as well as the DNA sensor cyclic GMP-AMP (cGAMP) synthase (cGAS). These receptors activate IRF3/7 and NF-?B signaling pathways to induce the expression of type I interferons (IFNs) and other cytokines firing antiviral responses within the cell.
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