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NPS-1034 Exerts Therapeutic Efficacy in Renal Cell Carcinoma Through Multiple Targets of MET, AXL, and TNFRSF1A Signaling in a Metastatic Model
1. Introduction Renal cell carcinoma (RCC) is one of the most lethal common urologic cancers. It accounts for 2.2% of all adult malignancies in global cancer statistics, with diagnoses made primarily between 55 and 75 years of age and a male-to-female incidence of 6.1 to 3.2, respectively. It is now among the top ten most frequently diagnosed malignancies [1,2,3,4,5,6]. Clear cell RCC (ccRCC) represents the most common histopathological diagnosis among RCC cancer-related deaths.
Anticancer potential of isoalantolactone in testicular cancer: an analysis of cytotoxicity, apoptosis, and signaling pathways
Research Paper Volume 16, Issue 19 pp 12820—12832 1 Department of Pathology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung 83301, Taiwan 2 School of Medicine, Chung Shan Medical University, Taichung 40201, Taiwan 3 Department of Urology, Chung Shan Medical University Hospital, Taichung 40201, Taiwan 4 Department of Urology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung 83301, Taiwan 5 Center...
Anticancer potential of isoalantolactone in testicular cancer: an analysis of cytotoxicity, apoptosis, and signaling pathways
Research Paper Volume 16, Issue 19 pp 12820—12832 1 Department of Pathology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung 83301, Taiwan 2 School of Medicine, Chung Shan Medical University, Taichung 40201, Taiwan 3 Department of Urology, Chung Shan Medical University Hospital, Taichung 40201, Taiwan 4 Department of Urology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung 83301, Taiwan 5 Center...
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