Christabel Xin Tan on Muck Rack

Christabel Xin Tan

As seen in: Nature
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Trimodal single-cell profiling of transcriptome, epigenome and 3D genome in complex tissues with scHiCAR - Nature Biotechnology

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By Xiaolin Wei, Yueyuan Xu, Dongchan Yang, Kyukwang Kim, Lizhi Yi, Wenzhe Luo, Xin Lin, Yu Xiang, Ashley Williams, Xiaotao Wang, Sweta Srivas, Christabel Xin Tan, Kan Zhang, Wei Li, Feng Yue, Z. Huang, Inkyung Jung, Yarui Diao
| Nature Verified
Abstract The three-dimensional (3D) organization of cis-regulatory elements (CREs) is critical in transcription control. However, capturing transcriptome, epigenome and 3D genome from the same single cells remains challenging. Here we present scHiCAR (single-cell Hi-C with assay for transposase-accessible chromatin and RNA sequencing), a plate-based combinatorial barcoding method that simultaneously profiles mRNA, open chromatin and chromosome conformation capture from the same cells.
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Astrocytic LRRK2 Controls Synaptic Connectivity through ERM Phosphorylation

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By Shiyi Wang, Dhanesh Sivadasan Bindu, Kristina Sakers, Christabel Xin Tan
| biorxiv.org
Thank you for your interest in spreading the word about bioRxiv. NOTE: Your email address is requested solely to identify you as the sender of this article. Your Email * Your Name * Send To * Enter multiple addresses on separate lines or separate them with commas. Message Subject (Your Name) has forwarded a page to you from bioRxiv Message Body (Your Name) thought you would like to see this page from the bioRxiv website.
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