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Christian Wesselborg

As seen in: BioRxiv, Cell Reports
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Articles

Daily oscillations of neuronal membrane capacitance

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By Daniel Severin, Johns Hopkins, Christian Wesselborg, Sofia Shirley
| Cell Reports Verified
Keywords Circadian oscillators capacitance cortex hippocampus pyramidal cells granule cells electrophysiology Research topic(s) CP: Neuroscience Introduction Capacitance is a so-called passive property of the membrane and is a determining factor of fundamental neuronal properties, such as action potential propagation speed,1 synaptic integration,2,3 and action potential firing frequency.4 As summarized in the following equation capacitance depends not only on the dielectric constant (ε) of...
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Daily membrane capacitance changes in mouse neurons

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By Daniel Severin, Cristian Moreno Verified, Trinh Tran, Christian Wesselborg
| BioRxiv
Abstract Capacitance of biological membranes is determined by the properties of the lipid portion of the membrane, as well as morphological features of a cell. In neurons, membrane capacitance is a determining factor of synaptic integration, action potential propagation speed and firing frequency due to its direct effect on the membrane time constant.
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