Christopher A. Guevara on Muck Rack

Christopher A. Guevara

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Grand Junction
As seen in: WeatherNation TV, Cell Reports, NewsBreak, JNeurosci, KJCT-TV (Grand Junction, CO), KKCO-TV (Grand Junction, CO)
Meteorologist. Ball State 2020 Alumni. Traveler, Explorer, Climber, Adventurer, Runner, Youtuber.
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Articles

Parkinson's LRRK2-G2019S risk gene mutation drives sex-specific behavioral and cellular adaptations to chronic variable stress

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By Christopher A. Guevara , Swati Gupta, Romario Thomas, Kumayl Alloo
| biorxiv.org
Abstract Anxiety is a psychiatric non-motor symptom of Parkinson's that can appear in the prodromal period, prior to significant loss of brainstem dopamine neurons and motor symptoms. Parkinson's-related anxiety affects females more than males, despite the greater prevalence of Parkinson's in males. How stress, anxiety and Parkinson's are related and the basis for a sex-specific impact of stress in Parkinson's are not clear.
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Parkinson’s-linked LRRK2-G2019S derails AMPAR trafficking, mobility and composition in striatum with cell-type and subunit specificity

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By Swati Gupta, Christopher A. Guevara , Alexander Tielemans
| biorxiv.org
INTRODUCTION Leucine-rich repeat kinase 2 (LRRK2), a multi-functional kinase, has been the subject of intense study since it was discovered that inherited, autosomal dominant mutations that increase its kinase activity also increase the risk for Parkinson’s (PD). Elevated LRRK2 levels or kinase activity, in the absence of mutation, also occur in patients with idiopathic PD (1, 2), suggesting that the enzyme is part of a common disease pathology.
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A sunny weekend is ahead with slow-warming temperatures

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By Christopher A. Guevara 
| KKCO-TV (Grand Junction, CO)
GRAND JUNCTION, Colo. (KKCO) - A look into our Friday: Throughout our Friday, we will see plenty of sunshine across the Western Slope, with dry conditions. Winter storm conditions have since ceased in the high country, but some mountain passes could still have slick and icy spots. Temperatures today are to sit in the lower 60s for Grand Junction, Montrose, Delta, and Cortez.
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