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Christopher Bartley

As seen in: Medium, The Startup, Nature, JAMA (The Journal of the American Medical Association), BioRxiv, Cell Press, Cell Reports Medicine, CR Fashion Book, Neurology, The Journal of Clinical Investigation and
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Articles

Convergent neuroimmune signaling underlying rapid antidepressant response to ketamine and psychedelics

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By Gregory Jones, Jessica Gilbert, Jenessa N Johnston, Nirmala Akula, Anton Schulmann, Miranda Arakelian, Shiyong Peng, Peixiong Yuan, Mani Yavi, Brandi Quintanilla, Abdel G. Elkahloun, Ruin Moaddel, Ioline D Henter, Dede Greenstein, Rodrigo Machado-Vieira, Christopher Bartley, Bashkim Kadriu, Moran Amit, Katy Rezvani, Mark D Kvarta, Francis J. McMahon, Carlos A. Jr., Ewurakua A. Winful
| Nature Verified
Abstract Despite distinct receptor targets, both ketamine and serotonergic psychedelics produce a rapid clinical response and share biological signatures that suggest convergence on common downstream molecular mediators.
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Brain-Immune Crosstalk in Mental Illness: The Path to Immunopsychiatry

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By Christopher Bartley, Pathophysiology Branch, Anna V. Molofsky
| Biological Psychiatry Verified
Get full text access Log in, subscribe or purchase for full access. References 1. Mullard, A. FDA approves 100th monoclonal antibody product Nat Rev Drug Discov. 2021; 20:491-495 2. Hachenberg, S. ∙ Russo, S.J. ∙ Cathomas, F. Immunity in rodent models of stress Biol Psychiatry. 2026; 99:936-948 3. Anderson, S.R. ∙ Jin, R.M. ∙ Molofsky, A.V. Neuroimmune mechanisms of neurodevelopmental disorders Biol Psychiatry. 2026; 99:949-959 4. van der Walt, K.
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Dynamic Cytokine Relationships Across the Blood-Brain Barrier in Humans and Non-Human Primates, Implications for Psychiatric Illness: A Systematic Review

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By Christopher Bartley
| Biological Psychiatry Verified
Keywords Psychiatric Illness Central Nervous System Blood Inflammation Cytokines Cerebrospinal Fluid Get full text access Log in, subscribe or purchase for full access. References 1. Louveau, A. ∙ Harris, T.H. ∙ Kipnis, J. Revisiting the Mechanisms of CNS Immune Privilege Trends Immunol. 2015; 36:569-577 2. Salvador, A.F. ∙ de Lima, K.A. ∙ Kipnis, J. Neuromodulation by the immune system: a focus on cytokines Nat Rev Immunol. 2021; 21:526-541 3. Zipp, F. ∙ Bittner, S.
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