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Chuan-Chung Chuang

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A materiobiology-inspired sericin nerve guidance conduit extensively activates regeneration-associated genes of Schwann cells for long-gap peripheral nerve repair

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By Hiroshi Senoo, Miho Iijima, Chuan-Chung Chuang, Ming-Yu Chiang
| ScienceDirect Verified
Peripheral nerve injury (PNI) mainly results from traffic accidents, fall injuries, tumor extirpation, and other types of traumas, leading to dysfunction of sensory and motor in the innervation zone and even severe disability [1], [2]. Damaged peripheral nerves can spontaneously regenerate at a rate of 1–3 mm daily [3], and short gaps (<8 mm) of injured nerves can be repaired through epineural anastomosis to achieve satisfactory nerve regeneration [4].
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