Chunying Han

4 DISCUSSION MCMs have been identified to contribute to tumorigenesis and tumour cell proliferation in various cancers.23, 24 As a member of MCMs, research on MCM10 has been increasing in recent years.

Dear Colleagues, The World Health Orginization has outlined a roadmap to a “world in which every woman, child and adolescent in every setting realizes their rights to physical and mental health and well-being, has social and economic opportunities, and is able to participate fully in shaping prosperous and sustainable societies.” In this bold new world, the future is transformed to ensure that every newborn, pregnancy, and child not only survives, but thrives.

1. Introduction Pathological fetal overgrowth, including macrosomia and large-for-gestational-age (LGA), is a clinically important reproductive health problem and has long-lasting metabolic impacts on the next generation [1,2,3]. The prevalence of macrosomia and LGA is approximately 1–20% and 4–22% worldwide and 3–14% and 7–22% in China, respectively [4,5,6,7].