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Chusi Wang on Muck Rack

Chusi Wang

As seen in: Nature
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Articles

Plasma proteomics framework predicts metabolic dysfunction-associated steatotic liver disease up to 16 years before onset

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By Shiyi Yu, Chunling Chen, Jing Feng, Qinming Li, Shuo Chen, Ruijie Zeng, Dongling Luo, Wentao Huang, Kexin Zhang, Yuying Ma, Lijun Zhang, Meijun Meng, Yanjun Wu, dong chen, Qizhou Lian, Felix Leung, Weihong Sha, Hao Chen, Chusi Wang
| Nature Verified
Abstract Metabolic dysfunction-associated steatotic liver disease (MASLD) is a global health challenge, yet preclinical identification remains difficult owing to a lack of reliable predictive tools. Here we show that a panel of five plasma proteins, FUOM, ACY1, KRT18, CDHR2 and GGT1, identified and validated across over 50,000 participants from the Southern UK, Northern UK, EPIC-Norfolk and Southern China cohorts, serves as a predictive signature for incident MASLD.
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