Circe E. McDonald on Muck Rack

Circe E. McDonald

As seen in: Cell Press
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Articles

West Nile Virus Infection Blocks Inflammatory Response and T Cell Costimulatory Capacity of Human Monocyte-Derived Dendritic Cells

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By Matthew Zimmerman, James Bowen, Circe E. McDonald
| asm.org
Cellular Response to Infection | Spotlight Matthew G. Zimmerman, James R. Bowen, Circe E. McDonald, Bali Pulendran, Mehul S. Suthar Bryan R. G. Williams, Editor DOI: 10.1128/JVI.00664-19 ABSTRACT West Nile virus (WNV) is a neurotropic flavivirus and the leading cause of mosquito-borne encephalitis in the United States. Recent studies in humans have found that dysfunctional T cell responses strongly correlate with development of severe WNV neuroinvasive disease.
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STAT5: a Target of Antagonism by Neurotropic Flaviviruses

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By Matthew Zimmerman, James Bowen, Circe E. McDonald, Ellen Young
| asm.org
Cellular Response to Infection | Spotlight Matthew G. Zimmerman, James R. Bowen, Circe E. McDonald, Ellen Young, Ralph S. Baric, Bali Pulendran, Mehul S. Suthar Bryan R. G. Williams, Editor DOI: 10.1128/JVI.00665-19 ABSTRACT Flaviviruses are a diverse group of arthropod-borne viruses responsible for numerous significant public health threats; therefore, understanding the interactions between these viruses and the human immune response remains vital.
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Zika Virus Infects Human Placental Macrophages

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By Kendra Quicke, James Bowen, Erica Johnson, Circe E. McDonald, Huailiang Ma
| Cell Press Verified
HCs and CTBs Are Permissive to Productive ZIKV Infection   Type I IFN and Pro-inflammatory Cytokines Are Produced in Response to ZIKV Infection   ZIKV Infection Provokes an Antiviral Immune Response in HCs and CTBs The present data demonstrate that primary HCs and CTBs isolated from full-term placentae are permissive to productive ZIKV infection by a contemporary strain currently circulating in the Americas.
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