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Claus Bachert

As seen in: Allergy - European Journal of Allergy and Clinical Immunology, Color Research & Application, Nature, Wiley, Wiley Online Library, ScienceDirect, Clinical and Translational Allergy, JAMA: Journal of the American Medical Association, The Lancet, Canadian Journal of Infectious Diseases & Medical Microbiology and
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Articles

The Unified Airway Hypothesis: Evidence From Specific Intervention With Anti-IL-5 Biologic Therapy

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By Claus Bachert
| Texas Medical Center
Faculty, Staff and Student Publications Publication Date 9-1-2023 Journal The Journal of Allergy and Clinical Immunology: In Practice DOI 10.1016/j.jaip.2023.05.011 Abstract The unified airway hypothesis proposes that upper and lower airway diseases reflect a single pathological process manifesting in different locations within the airway. Functional, epidemiological, and pathological evidence has supported this well-established hypothesis for some time.
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Asthma and lower airway disease Skin tape strips identify age-specific immune, metabolic, and barrier dysregulation signatures in children, adolescents, and adults with allergic asthma

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By Jens Schreiber, Claus Bachert, Fredrika Koskimäki
| ScienceDirect Verified
Asthma and lower airway disease Skin tape strips identify age-specific immune, metabolic, and barrier dysregulation signatures in children, adolescents, and adults with allergic asthma Author links open overlay panelDaniel Liu BA a, Madeline Kim MD, MS a, Ester Del Duca MD, PhD a, Jonathan Bar MD a, Megan Lau BS a, Joseph Largen BS a, Ioana Agache MD, PhD b, Emma Guttman-Yassky MD, PhD a Show more Background Allergic asthma pathogenesis encompasses systemic immune, metabolic, and epithelial...
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TLR4+group 2 innate lymphoid cells contribute to persistent type 2 immunity in airway diseases - Nature Communications

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By Claus Bachert, Feng Lan, Chengshuo Wang, Zaichuan Wang
| Nature Verified
Abstract Group 2 innate lymphoid cells (ILC2s) directly contribute to local inflammation in type 2 inflammatory airway diseases. Here, we identify ILC2 subsets by single cell RNA sequencing in chronic rhinosinusitis with nasal polyps (CRSwNP) and in a memory inflammatory mouse model.
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