Updated on 12th Jan 2026 The US Food and Drug Administration (FDA) has approved Novo Nordisk’s pill Wegovy, which is now available in US pharmacies. Clinical trials showed that patients achieved similar weight loss with the oral medication as with the injectable GLP-1 drug Wegovy. In a 64-week phase 3 clinical trial, the Wegovy pills demonstrated a mean weight loss of 16.6%, with a third of the 1,300 participants experiencing a weight loss of 20% or greater.