Craig C. Mello on Muck Rack

Craig C. Mello

Rhode Island
As seen in: Nature, PLOS, Boston Business Journal, Cell Press, The Modesto Bee, The Pew Trusts, Genetics, Business People
We can do this people! Make planet earth great again! Love each other, question everything! Stop complaining and start Voting! Not every 4 years, every 2! 🤟
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Articles

Nobel laureates warn federal funding cuts threaten Mass. research jobs - Boston Business Journal

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By Victor Ambros, Craig C. Mello
| Boston Business Journal Verified
UMass Chan RNA researchers and Nobel Prize Winners Victor Ambros, left, and Craig Mello. Faith Ninivaggi Preview this article 1 min Two Nobel laureates warn that delayed federal grants are forcing layoffs and halting research at Massachusetts' only public medical school.
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Casein kinase II promotes piRNA production through direct phosphorylation of USTC component TOFU-4

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By Craig C. Mello, Gangming Zhang, Chunwei Zheng
| biorxiv.org
Abstract Piwi-interacting RNAs (piRNAs) are genomically encoded small RNAs that engage Piwi Argonaute proteins to direct mRNA surveillance and transposon silencing. Despite advances in understanding piRNA pathways and functions, how the production of piRNA is regulated remains elusive. Here, using a genetic screen, we identify casein kinase II (CK2) as a factor required for piRNA pathway function.
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The CERV protein of Cer1, a C. elegans LTR retrotransposon, is required for nuclear export of viral genomic RNA and can form giant nuclear rods

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By Bing Sun, Haram Kim, Craig C. Mello, James R Priess
| PLOS
CERV rods and the nucleolus To understand how CERV rods form, we searched for potential intermediate structures. Rings of CERV were frequently visible in germ nuclei, and we considered whether these might template rod formation. However, optical Z-stacks showed that all rings scored were cross-sections of long rods (n = 76; Fig 5B, panel 1; see also S2 Video).
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