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Cristina Barillà on Muck Rack

Cristina Barillà

As seen in: Cell Stem Cell
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Articles

Derivation of Airway Basal Stem Cells from Human Pluripotent Stem Cells

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By Finn Hawkins, Shingo Suzuki, Mary Lou Beermann, Cristina Barillà
| Cell Stem Cell Verified
Highlights • Directed differentiation of human iPSCs generates airway basal cells (“iBCs”) • iBCs self-renew and display multipotent differentiation in vitro and in vivo • By single-cell RNA-seq, iBCs are highly similar to adult primary airway basal cells • iBCs enable modeling of acquired and genetic airway diseases Summary The derivation of tissue-specific stem cells from human induced pluripotent stem cells (iPSCs) would have broad reaching implications for regenerative medicine.
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