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Cuiying Chen

As seen in: BioRxiv, The Journal of Biological Chemistry
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Articles

A nanobody-enzyme fusion protein targeting PD-L1 and sialic acid exerts anti-tumor effects by affecting tumor associated macrophages

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By Yongliang Tong, Xinrong Lu, Runqiu Chen, Cuiying Chen
| BioRxiv
Abstract Cancer cells employ various mechanisms to evade immune surveillance. Their surface features, including a protective "sugar coat" and immune checkpoints like PD-L1 (programmed death ligand 1), can impede immune cell recognition. Sialic acids, which carry negative charges, may hinder cell contact through electrostatic repulsion, while PD-L1 transmits immunosuppressive signals to T cells.
Open in Who Shared Issue with article?

miR-26a mediates LC-PUFA biosynthesis by targeting the Lxrα-Srebp1 pathway in the marine teleost Siganus canaliculatus

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By Cuiying Chen, Shuqi Wang, YU HU, Mei Zhang
| The Journal of Biological Chemistry Verified
Cuiying Chen1, Shuqi Wang1, Yu Hu1, Mei Zhang1, Xianda He1, Cuihong You1, Xiaobo Wen2, Óscar Monroig3, Douglas R.
Open in Who Shared Issue with article?

miR-26a mediates LC-PUFA biosynthesis by targeting the Lxrα-Srebp1 pathway in the marine teleost Siganus canaliculatus

|
By Cuiying Chen, Shuqi Wang, YU HU, Mei Zhang
| The Journal of Biological Chemistry Verified
Cuiying Chen1, Shuqi Wang1, Yu Hu2, Mei Zhang1, Xianda He1, Cuihong You1, Xiaobo Wen3, Oscar Monroig4, Douglas R.
Open in Who Shared Issue with article?
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