Cynthia McMurray

Abstract Genome-wide association studies (GWAS) have provided strong evidence that modifiers of CAG tract length have a crucial influence on Huntington disease onset, but somatic expansion alone may not be sufficient to drive neuronal death. Here, we report that DSBs drive neuropathology in male HdhQ(150/150) mice, regardless of somatic expansion of the inherited disease allele.

Advertisement 1 Healthy Living Article content We live in a world in which we want/need fast fixes. We have no tolerance for anything that feels uncomfortable, including physical pain, so at the first sign of it, we pop a pill or find other ways to numb the sensation. While not wanting to feel pain is completely understandable, we also need to look at the risks involved with how we choose to deal with that pain.

If your doctor told you that you have acromegaly, would you know what it is? Likely not, according to Dr. Ali Imran, an endocrinologist at the QEII Health Sciences Centre and professor of medicine at Dalhousie University. Dr. Imran, who is also the co-chair of endocrinology for the Halifax Neuropituitary Program, says not many people have heard of this relatively rare disease or how it affects people. “It can develop in childhood, but it typically develops in the 20s or early 30s.