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Daisylyn Senna Tan on Muck Rack

Daisylyn Senna Tan

As seen in: Nature, Science Magazine
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Articles

The emergence of Sox and POU transcription factors predates the origins of animal stem cells - Nature Communications

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By Ya Gao, Daisylyn Senna Tan, Mathias Girbig, Qianwen Xie, Sik Yin Ho, Vlad Cojocaru, Jian Yan, Alex de Mendoza
| Nature Verified
Abstract Stem cells are a hallmark of animal multicellularity. Sox and POU transcription factors are associated with stemness and were believed to be animal innovations, reported absent in their unicellular relatives. Here we describe unicellular Sox and POU factors. Choanoflagellate and filasterean Sox proteins have DNA-binding specificity similar to mammalian Sox2.
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An engineered Sox17 induces somatic to neural stem cell fate transitions independently from pluripotency reprogramming

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By Matthew Graus, Ya Gao, Jakob Langer, Markus Holzner, Yuhua Huang, Mathias François, Ralf Jauch, Mingxi Weng, Haoqing Hu, Daisylyn Senna Tan, Shimiao Ren
| Science Magazine Verified
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