Dalton Hughes on Muck Rack

Dalton Hughes

As seen in: Gridiron Now, Nature, Corporate Counsel, Cell Press, Lexology, JURIST, Mondaq, TexAgs, LexBlog, Practice Source
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Articles

Long-term editing of brain circuits using an engineered electrical synapse

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By Elizabeth Ransey, Gwenaelle Thomas, Agustin Almoril-Porras, Ryan Bowman, Elise Adamson, Kathryn K. Walder-Christensen, Jesse White Verified, Dalton Hughes, Hannah Schwennesen, Kay M. Tye, Stephen D. Mague, Longgang Niu, Zhao-Wen Wang, Daniel Colón-Ramos, Rainbo Hultman, Nenad Bursac, Kafui Dzirasa, Caly Ferguson
| Nature Verified
Abstract Electrical signalling across distinct populations of brain cells underpins cognitive and emotional function. However, approaches that selectively regulate electrical signalling between two cellular components of a mammalian neural circuit remain sparse. Here we engineered an electrical synapse composed of two connexin proteins1 found in Morone americana (white perch fish)—connexin 34.7 and connexin 35—to accomplish mammalian circuit modulation.
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U.S. Copyright Office Releases Part 2 Of Artificial Intelligence Report, Clarifying Copyrightability Of Generative AI Outputs

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By William H. Frankel, Sari Depreeuw, Dalton Hughes, Joachim Steinberg
| Mondaq
Key takeaway#1 The Copyright Office found that existing principles of copyright law are still flexible enough to apply to generative AI technology. Key takeaway#2 Copyright protection can apply if human-authored work is perceptible in an AI output, if a custom AI is used as a tool to expand upon a specific protectable human input, or if a human makes creative arrangements or modifications of the output.
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A widespread electrical brain network encodes anxiety in health and depressive states

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By Dalton Hughes, Michael Klein, Gwenaelle Thomas, Kathryn Katsue Walder-Christensen
| biorxiv.org
Abstract In rodents, anxiety is charactered by heightened vigilance during low-threat and uncertain situations. Though activity in the frontal cortex and limbic system are fundamental to supporting this internal state, the underlying network architecture that integrates activity across brain regions to encode anxiety across animals and paradigms remains unclear.
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