Damian Bartuzi

Introduction Click to copy section linkSection link copied! Monoamine dopamine (DA) acts via G protein-coupled dopamine receptors to modulate physiological processes including motor function, reward mechanisms, and the learning process. (1) This family of five receptors (D1–5R) is divided into the Golf/s -coupled D1-like receptors (D1R and D5R) and the D2-like (D2R, D3R, and D4R) that couple to the Gαi/o/z family of G proteins to inhibit cAMP production.

Introduction Click to copy section linkSection link copied! Cancer remains a significant public health issue and ranks as the second most common cause of death. The increasing prevalence of prostate cancer (PCa) from 2014 to 2019 is particularly worrisome after a downward trend spanning two decades. (1) While considerable progress has been made in PCa treatment options, the need for more potent therapies remains pressing.

Conflict of interests The authors declare no conflicts of interest. Supporting Information As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors.